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Theoretical Modelling

By GlasgowUni 2011

During our project DISColi, regarding Bio-photolithography in biofilms, we created mathematical models involving Ranaspumin-2 and its rate of diffusion through a biofilm. We are presenting our findings in Figure 1 and Table 1. Also, due to the mode of action of Ranaspumin-2 the attainable spatial resolution seems to be less than 0.09 mm. For more information, please visit GlasgowUni 2011 Wiki

Figure.1. Relative One-dimensional Diffusion of (a)Ranaspumin-2 at certain points in time and (b)Ranaspumin-2 within first 60 min. Threshold indicates critical concentration required for the molecule to work.

(a)

(b)

Table 1. Details on Ranaspumin-2

Name of molecule	Length (a.a.)	Molecular weight (g/mol)	Diffusion rate (mm2/min)	Critical concentration (molecules)	Translation rate (molecule/min)	Achieving Critical Concentration (min)
Ranaspumin-2	98	11287	1.68*10-4	374	105.3	3